The curremt bottom 5 will be the same at the end of the season, as they are getting cut adrift. Predictable really - the three promoted teams and the the 2 poor teams from last season. Any one of the 5 could finish bottom, but my money is on Toulouse.
If we, Huddersfield or York finish bottom then either will be definately be down to the Championship. If Toulouse or Bradford finish bottom it will still be Cas, Huddersfield or York who go down, as they will fiddle the IMG gradings to make sure Toulouse, Bradford and London are in SL next season.